Negative Pressure Ventilation for High-Care & High-Dependency Healthcare

Creating a Negative Pressure Room

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Exeon CleanCair™ has been designed to create a negative pressure room and safely manage contaminated airflow in critical care environments. This self-contained ventilation system has been developed from proven techniques and equipment. It offers a readily-available solution for negative pressure, ultra HEPA filtration of contaminated air and increased air changes in medical environments.

Key Benefits of the Exeon CleanCair™ system

  • Safe-Change HEPA housing for total infection-free filter maintenance. 
  • H14 HEPA filter removes infectious particles down to 0.3 µm with an efficiency >99.999%
  • Each unit delivers up to 5,000m3/hr to enable maximum air changes.
  • Acoustically treated unit for minimum noise levels
  • The unit can be retrofitted to existing AHU ducting to provide HEPA filtered return air or installed as a standalone system.
negative pressure isolation

Reasons to use a CleanCair™ unit in an Isolation Room / HDU / Other Critical Isolation Zones:

negative pressure ventilation
  • Filtration

    A HEPA filter will capture respiratory droplets which are typically >5 to 10 µm and other small particles which viruses can attach to.

  • Ventilation

    Creating a healthy and well-ventilated environment is critical (and a legal requirement) for both staff and patients. Good ventilation keeps NO2, CO2 and CO to satisfactory levels. It also greatly reduces the chances of infection (e.g. COVID-19), as there is air movement in the room. Public Health England’s NHS COVID-19 infection prevention and control guidance document states that in wards and single rooms there should be a minimum of 6 air changes per hour.

  • Negative Pressure Room

    Maintaining a negative air pressure room prevents the room air from escaping into the surrounding atmosphere and potentially spreading infection. PHE’s NHS COVID-19 infection prevention and control guidance document states that in a negative pressure room there should be a minimum of 12 air changes per hour.

  • Fire Prevention

    According to the NHS NOVEL CORONAVIRUS SOP dated March 2020, the use of medical oxygen can build up in confined spaces, causing a serious fire risk.

Negative Pressure Isolation Room

A negative pressure isolation room is widely used in environments where airborne contaminants need to be prevented from leaving. In medical establishments their use can include:

  • Airborne Infection Isolation Rooms (AIIRs)
  • AIIR anterooms and toilets
  • Triage areas
  • Temporary Mortuaries
  • Emergency Room waiting areas
  • ER decontamination areas


negative pressure ventilation

Fan flow volume is calculated by multiplying the room volume by the required number of air changes per unit time. A small room to be well ventilated requires 6-10 air changes per hour. A negative pressure room to be well ventilated requires over 12 changes per hour.


A room 6m x 4m x 2.5m is 60m3.
For 10 air changes per hour = 60 x 10 = 600 m3/hr fan flow rate.
A standard CleanCair™ unit will handle up to 3000 m3/hr or 5 rooms this size.

About the CleanCair™ System

The CleanCair™ negative pressure room system allows for rapid installation of a self-contained fan/filter unit with a Safe-Change HEPA filter unit to ensure that the filter can be changed with the minimum of risk to maintenance personnel.

The system is very simple and cost-effective, ventilation can be provided to a number of rooms very quickly and can be easily moved to another area. The unit can be retrofitted to existing AHU ducting to provide HEPA filtered return air.

There are two standard units but systems can be bespoke to suit any situation.


The unit is also available in a vertical format and can be made suitable for exterior mounting